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Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring
Ki-67 assessment is a key step in the diagnosis of neuroendocrine neoplasms (NENs) from all anatomic locations. Several challenges exist related to quantifying the Ki-67 proliferation index due to lack of method standardization and inter-reader variability. The application of digital pathology coupl...
Autores principales: | Luchini, Claudio, Pantanowitz, Liron, Adsay, Volkan, Asa, Sylvia L., Antonini, Pietro, Girolami, Ilaria, Veronese, Nicola, Nottegar, Alessia, Cingarlini, Sara, Landoni, Luca, Brosens, Lodewijk A., Verschuur, Anna V., Mattiolo, Paola, Pea, Antonio, Mafficini, Andrea, Milella, Michele, Niazi, Muhammad K., Gurcan, Metin N., Eccher, Albino, Cree, Ian A., Scarpa, Aldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174054/ https://www.ncbi.nlm.nih.gov/pubmed/35249100 http://dx.doi.org/10.1038/s41379-022-01055-1 |
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