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Single-cell RNA sequencing reveals evolution of immune landscape during glioblastoma progression

Glioblastoma (GBM) is an incurable primary malignant brain cancer hallmarked with a substantial protumorigenic immune component. Knowledge of the GBM immune microenvironment during tumor evolution and standard of care treatments is limited. Using single-cell transcriptomics and flow cytometry, we un...

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Detalles Bibliográficos
Autores principales: Yeo, Alan T., Rawal, Shruti, Delcuze, Bethany, Christofides, Anthos, Atayde, Agata, Strauss, Laura, Balaj, Leonora, Rogers, Vaughn A., Uhlmann, Erik J., Varma, Hemant, Carter, Bob S., Boussiotis, Vassiliki A., Charest, Al
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174057/
https://www.ncbi.nlm.nih.gov/pubmed/35624211
http://dx.doi.org/10.1038/s41590-022-01215-0