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NLRP3 licenses NLRP11 for inflammasome activation in human macrophages

Intracellular sensing of stress and danger signals initiates inflammatory innate immune responses by triggering inflammasome assembly, caspase-1 activation and pyroptotic cell death as well as the release of interleukin 1β (IL-1β), IL-18 and danger signals. NLRP3 broadly senses infectious patterns a...

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Detalles Bibliográficos
Autores principales: Gangopadhyay, Anu, Devi, Savita, Tenguria, Shivendra, Carriere, Jessica, Nguyen, Huyen, Jäger, Elisabeth, Khatri, Hemisha, Chu, Lan H., Ratsimandresy, Rojo A., Dorfleutner, Andrea, Stehlik, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174058/
https://www.ncbi.nlm.nih.gov/pubmed/35624206
http://dx.doi.org/10.1038/s41590-022-01220-3