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NLRP3 licenses NLRP11 for inflammasome activation in human macrophages
Intracellular sensing of stress and danger signals initiates inflammatory innate immune responses by triggering inflammasome assembly, caspase-1 activation and pyroptotic cell death as well as the release of interleukin 1β (IL-1β), IL-18 and danger signals. NLRP3 broadly senses infectious patterns a...
Autores principales: | Gangopadhyay, Anu, Devi, Savita, Tenguria, Shivendra, Carriere, Jessica, Nguyen, Huyen, Jäger, Elisabeth, Khatri, Hemisha, Chu, Lan H., Ratsimandresy, Rojo A., Dorfleutner, Andrea, Stehlik, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174058/ https://www.ncbi.nlm.nih.gov/pubmed/35624206 http://dx.doi.org/10.1038/s41590-022-01220-3 |
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