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Loss of core-fucosylation of SPARC impairs collagen binding and contributes to COPD
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with high morbidity and mortality worldwide. Although several mechanisms to account for deleterious immune effects were proposed, molecular description for the underlying alveolar structural alterations for COPD is lacking. H...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174126/ https://www.ncbi.nlm.nih.gov/pubmed/35670884 http://dx.doi.org/10.1007/s00018-022-04381-4 |