Cargando…

Loss of core-fucosylation of SPARC impairs collagen binding and contributes to COPD

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease with high morbidity and mortality worldwide. Although several mechanisms to account for deleterious immune effects were proposed, molecular description for the underlying alveolar structural alterations for COPD is lacking. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Tsai-Jung, Wang, Sheng-Hung, Chen, Eric Sheng-Wen, Tsai, Hsiu-Hui, Chang, Yi-Chieh, Tseng, Yi-Hsin, Yu, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174126/
https://www.ncbi.nlm.nih.gov/pubmed/35670884
http://dx.doi.org/10.1007/s00018-022-04381-4