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JMJD3 intrinsically disordered region links the 3D-genome structure to TGFβ-dependent transcription activation

Enhancers are key regulatory elements that govern gene expression programs in response to developmental signals. However, how multiple enhancers arrange in the 3D-space to control the activation of a specific promoter remains unclear. To address this question, we exploited our previously characteriz...

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Detalles Bibliográficos
Autores principales: Vicioso-Mantis, Marta, Fueyo, Raquel, Navarro, Claudia, Cruz-Molina, Sara, van Ijcken, Wilfred F. J., Rebollo, Elena, Rada-Iglesias, Álvaro, Martínez-Balbás, Marian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174158/
https://www.ncbi.nlm.nih.gov/pubmed/35672304
http://dx.doi.org/10.1038/s41467-022-30614-y