Dynamic insights into the effects of nonsynonymous polymorphisms (nsSNPs) on loss of TREM2 function

Single nucleotide variations in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) are associated with many neurodegenerative diseases, including Nasu-Hakola disease (NHD), frontotemporal dementia (FTD), and late-onset Alzheimer's disease because they disrupt ligand binding to the extrace...

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Detalles Bibliográficos
Autores principales: Dash, Raju, Munni, Yeasmin Akter, Mitra, Sarmistha, Choi, Ho Jin, Jahan, Sultana Israt, Chowdhury, Apusi, Jang, Tae Jung, Moon, Il Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174165/
https://www.ncbi.nlm.nih.gov/pubmed/35672339
http://dx.doi.org/10.1038/s41598-022-13120-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174165/
https://www.ncbi.nlm.nih.gov/pubmed/35672339
http://dx.doi.org/10.1038/s41598-022-13120-5

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