Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer

BACKGROUND: To understand the relationship between key non-canonical NF-κB kinase IKK-alpha(α), tumour mutational profile and survival in primary colorectal cancer. METHODS: Immunohistochemical expression of IKKα was assessed in a cohort of 1030 patients who had undergone surgery for colorectal canc...

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Detalles Bibliográficos
Autores principales: Patel, Meera, Pennel, Kathryn A. F., Quinn, Jean A., Hood, Hannah, Chang, David K., Biankin, Andrew V., Rebus, Selma, Roseweir, Antonia K., Park, James H., Horgan, Paul G., McMillan, Donald C., Edwards, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174220/
https://www.ncbi.nlm.nih.gov/pubmed/35173303
http://dx.doi.org/10.1038/s41416-022-01729-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174220/
https://www.ncbi.nlm.nih.gov/pubmed/35173303
http://dx.doi.org/10.1038/s41416-022-01729-2

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