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Subfascial infiltration of 0.5% ropivacaine, but not 0.25% ropivacaine, exacerbates damage and inflammation in surgically incised abdominal muscles of rats

Ropivacaine-induced myotoxicity in surgically incised muscles has not been fully investigated. We evaluated the effects of infiltration anesthesia with ropivacaine on damage, inflammation and regeneration in the incised muscles of rats undergoing laparotomy. Ropivacaine or saline was infiltrated bel...

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Detalles Bibliográficos
Autores principales: Shen, Dandan, Sugiyama, Yuki, Ishida, Kumiko, Fuseya, Satoshi, Ishida, Takashi, Kawamata, Mikito, Tanaka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174254/
https://www.ncbi.nlm.nih.gov/pubmed/35672375
http://dx.doi.org/10.1038/s41598-022-13628-w