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Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade

AIMS/HYPOTHESIS: Immunomodulators blocking cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) or programmed death-ligand 1 (PD-L1) have improved the treatment of a broad spectrum of cancers. These immune checkpoint inhibitors (ICIs) reactivate the immune...

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Detalles Bibliográficos
Autores principales: Kawada-Horitani, Emi, Kita, Shunbun, Okita, Tomonori, Nakamura, Yuto, Nishida, Hiroyuki, Honma, Yoichi, Fukuda, Shiro, Tsugawa-Shimizu, Yuri, Kozawa, Junji, Sakaue, Takaaki, Kawachi, Yusuke, Fujishima, Yuya, Nishizawa, Hitoshi, Azuma, Miyuki, Maeda, Norikazu, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174328/
https://www.ncbi.nlm.nih.gov/pubmed/35511238
http://dx.doi.org/10.1007/s00125-022-05708-3