Cellular Heterogeneity and Cooperativity in Glioma Persister Cells Under Temozolomide Treatment

We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode labeling to follow cell population evolution during temozolomide treatment. We...

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Detalles Bibliográficos
Autores principales: Rabé, Marion, Fonteneau, Lucie, Oliver, Lisa, Morales-Molina, Alvaro, Jubelin, Camille, Garcia-Castro, Javier, Heymann, Dominique, Gratas, Catherine, Vallette, François M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174429/
https://www.ncbi.nlm.nih.gov/pubmed/35693929
http://dx.doi.org/10.3389/fcell.2022.835273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174429/
https://www.ncbi.nlm.nih.gov/pubmed/35693929
http://dx.doi.org/10.3389/fcell.2022.835273

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