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Cellular Heterogeneity and Cooperativity in Glioma Persister Cells Under Temozolomide Treatment
We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode labeling to follow cell population evolution during temozolomide treatment. We...
Autores principales: | Rabé, Marion, Fonteneau, Lucie, Oliver, Lisa, Morales-Molina, Alvaro, Jubelin, Camille, Garcia-Castro, Javier, Heymann, Dominique, Gratas, Catherine, Vallette, François M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174429/ https://www.ncbi.nlm.nih.gov/pubmed/35693929 http://dx.doi.org/10.3389/fcell.2022.835273 |
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