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A cocktail of human monoclonal antibodies broadly neutralizes North American rabies virus variants as a promising candidate for rabies post-exposure prophylaxis

Human rabies remains a globally significant public health problem. Replacement of polyclonal anti-rabies immunoglobulin (RIG), a passive component of rabies post-exposure prophylaxis (PEP), with a monoclonal antibody (MAb), would eliminate the cost and availability constraints associated with RIG. O...

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Detalles Bibliográficos
Autores principales: Ejemel, Monir, Smith, Todd G., Greenberg, Lauren, Carson, William C., Lowe, David, Yang, Yong, Jackson, Felix R., Morgan, Clint N., Martin, Brock E., Kling, Chantal, Hutson, Christina L., Gallardo-Romero, Nadia, Ellison, James A., Moore, Susan, Buzby, Adam, Sullivan-Bolyai, John, Klempner, Mark, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174473/
https://www.ncbi.nlm.nih.gov/pubmed/35672343
http://dx.doi.org/10.1038/s41598-022-13527-0