Biomarkers of response to PD-1 pathway blockade

The binding of T cell immune checkpoint proteins programmed death 1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) to their ligands allows immune evasion by tumours. The development of therapeutic antibodies, termed checkpoint inhibitors, that bind these molecules or their ligands,...

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Detalles Bibliográficos
Autores principales: Li, Hanxiao, van der Merwe, P. Anton, Sivakumar, Shivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174485/
https://www.ncbi.nlm.nih.gov/pubmed/35228677
http://dx.doi.org/10.1038/s41416-022-01743-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174485/
https://www.ncbi.nlm.nih.gov/pubmed/35228677
http://dx.doi.org/10.1038/s41416-022-01743-4

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