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Comparative Analysis of Single-Cell Transcriptome Data Reveals a Novel Role of Keratinocyte-Derived IL-23 in Psoriasis

Psoriasis, a common inflammatory skin disease, is critically dependent on the IL-23/IL-17 cytokine axis. Although immune cell-derived IL-23 is generally associated with the disease pathogenesis, there have been reports of IL-23 production in keratinocytes. To determine the presence and potential rol...

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Detalles Bibliográficos
Autores principales: Park, Young Joon, Kim, Yul Hee, Lee, Eun-So, Kim, You Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174585/
https://www.ncbi.nlm.nih.gov/pubmed/35693818
http://dx.doi.org/10.3389/fimmu.2022.905239