Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model

INTRODUCTION: Studies have identified the presence of M1 and M2 macrophages (Mϕ) in injured intervertebral discs (IVDs). However, the origin and polarization-regulatory factor of M2 Mϕ are not fully understood. TGF-β is a regulatory factor for M2 polarization in several tissues. Here, we investigate...

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Detalles Bibliográficos
Autores principales: Kawakubo, Ayumu, Miyagi, Masayuki, Yokozeki, Yuji, Nakawaki, Mitsufumi, Takano, Shotaro, Satoh, Masashi, Itakura, Makoto, Inoue, Gen, Takaso, Masashi, Uchida, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174651/
https://www.ncbi.nlm.nih.gov/pubmed/35592891
http://dx.doi.org/10.1177/03946320221103792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174651/
https://www.ncbi.nlm.nih.gov/pubmed/35592891
http://dx.doi.org/10.1177/03946320221103792

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