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Ceramide Aminoethylphosphonate as a New Molecular Target for Pore-Forming Aegerolysin-Based Protein Complexes

Ostreolysin A6 (OlyA6) is a 15 kDa protein produced by the oyster mushroom (Pleurotus ostreatus). It belongs to the aegerolysin family of proteins and binds with high affinity to the insect-specific membrane sphingolipid, ceramide phosphoethanolamine (CPE). In concert with its partnering protein wit...

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Detalles Bibliográficos
Autores principales: Balbi, Teresa, Trenti, Francesco, Panevska, Anastasija, Bajc, Gregor, Guella, Graziano, Ciacci, Caterina, Canonico, Barbara, Canesi, Laura, Sepčić, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174665/
https://www.ncbi.nlm.nih.gov/pubmed/35693554
http://dx.doi.org/10.3389/fmolb.2022.902706