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The “Loss” of Perineuronal Nets in Alzheimer's Disease: Missing or Hiding in Plain Sight?

Perineuronal nets (PNNs) are chondroitin-sulfate glycosaminoglycan (CS-GAG) containing extracellular matrix structures that assemble around neurons involved in learning, memory, and cognition. Owing to the unique patterning of negative charges stemming from sulfate modifications to the attached CS-G...

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Detalles Bibliográficos
Autores principales: Scarlett, Jarrad M., Hu, Shannon J., Alonge, Kimberly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174696/
https://www.ncbi.nlm.nih.gov/pubmed/35694184
http://dx.doi.org/10.3389/fnint.2022.896400