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Cholyl 1,3,4-oxadiazole hybrid compounds: design, synthesis and antimicrobial assessment

A new chemical library based on the hybridization of cholic acid with the heterocyclic moiety 1,3,4-oxadizole was synthesized, and tested for antimicrobial activity against Gram-positive, Gram-negative bacteria, and fungi. Among the synthesized compounds, the most potent derivatives against S. aureu...

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Detalles Bibliográficos
Autores principales: Rasras, Anas J, El-Naggar, Mohamed, Safwat, Nesreen A, Al-Qawasmeh, Raed A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174839/
https://www.ncbi.nlm.nih.gov/pubmed/35706993
http://dx.doi.org/10.3762/bjoc.18.63