Cargando…
Anticancer Efficacy and Mechanisms of a Dual Targeting of Norepinephrine Transporter and Thyrointegrin αvβ3 Antagonist in Neuroblastoma
Background: In neuroendocrine tumors, the norepinephrine transporter (NET) is very active and has been exploited for diagnostic imaging purposes and/or therapy with localized radiotherapy. Integrin αvβ3 is generously expressed by and/or activated on cancer cells, but not by nonmalignant cells. Purpo...
Autores principales: | Godugu, Kavitha, Karakus, Ozlem O., Fujioka, Kazutoshi, Glinsky, Gennadi V., Mousa, Shaker A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174855/ https://www.ncbi.nlm.nih.gov/pubmed/35711848 http://dx.doi.org/10.7150/jca.72522 |
Ejemplares similares
-
Discovery of novel thyrointegrin αvβ3 antagonist fb-PMT (NP751) in the management of human glioblastoma multiforme
por: Godugu, Kavitha, et al.
Publicado: (2022) -
Triazole Modified Tetraiodothyroacetic Acid Conjugated to Polyethylene Glycol, a Thyrointegrin α(v)β(3) Antagonist as a Radio- and Chemo-Sensitizer in Pancreatic Cancer
por: Sudha, Thangirala, et al.
Publicado: (2022) -
Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin α(v)β(3) antagonist
por: Fujioka, Kazutoshi, et al.
Publicado: (2022) -
Anti-Cancer Activities of Thyrointegrin α(v)β(3) Antagonist Mono- and Bis-Triazole Tetraiodothyroacetic Acid Conjugated via Polyethylene Glycols in Glioblastoma
por: Godugu, Kavitha, et al.
Publicado: (2021) -
Targeting Thyrointegrin αvβ3 Using Fluorobenzyl Polyethylene Glycol Conjugated Tetraiodothyroacetic Acid (NP751) in Acute Myeloid Leukemia
por: Darwish, Noureldien H. E., et al.
Publicado: (2022)