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Hexokinase 2 Promotes Cell Proliferation and Tumor Formation through the Wnt/β-catenin Pathway-mediated Cyclin D1/c-myc Upregulation in Epithelial Ovarian Cancer

Background: HK2 is reported as a key mediator of aerobic glycolysis, associating with the malignant growth in many types of cancers. Methods: In this study, stimulation of HK2 expression was observed in ovarian carcinoma tissues, comparing with the normal ovarian tissues. Results: Both of in vitro a...

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Detalles Bibliográficos
Autores principales: Liu, Xian, Zuo, Xiaohang, Sun, Xiaoli, Tian, Xueye, Teng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174861/
https://www.ncbi.nlm.nih.gov/pubmed/35711830
http://dx.doi.org/10.7150/jca.71894