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RPL17 Promotes Colorectal Cancer Proliferation and Stemness through ERK and NEK2/β-catenin Signaling Pathways

Aims: Ribosomal protein L17 (RPL17), a 60S subunit component, is up-regulated in colorectal cancer (CRC). However, its oncogenic role in CRC progression remains unexplored. Thus, we aimed to investigate the effect of RPL17 targeting on CRC in vitro and in vivo and whether RPL17 gained an extra-ribos...

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Detalles Bibliográficos
Autores principales: Ko, Min Ji, Seo, Yu-Ri, Seo, Daekwan, Park, So-Young, Seo, Ji Hae, Jeon, Eun-Hye, Kim, Sang-Woo, Park, Keon Uk, Koo, Deog-Bon, Kim, Shin, Bae, Jae-Hoon, Song, Dae-Kyu, Cho, Chi Heum, Kim, Kwang Seok, Lee, Yun-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174872/
https://www.ncbi.nlm.nih.gov/pubmed/35711835
http://dx.doi.org/10.7150/jca.69428