Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment

Batten disease is unique among lysosomal storage disorders for the early and profound manifestation in the central nervous system, but little is known regarding potential neuron-specific roles for the disease-associated proteins. We demonstrate substantial overlap in the protein interactomes of thre...

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Detalles Bibliográficos
Autores principales: Rechtzigel, Mitchell J., Meyerink, Brandon L., Leppert, Hannah, Johnson, Tyler B., Cain, Jacob T., Ferrandino, Gavin, May, Danielle G., Roux, Kyle J., Brudvig, Jon J., Weimer, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174988/
https://www.ncbi.nlm.nih.gov/pubmed/35692423
http://dx.doi.org/10.3389/fnins.2022.834780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174988/
https://www.ncbi.nlm.nih.gov/pubmed/35692423
http://dx.doi.org/10.3389/fnins.2022.834780

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