Integrin-Linked Kinase Expression Characterizes the Immunosuppressive Tumor Microenvironment in Colorectal Cancer and Regulates PD-L1 Expression and Immune Cell Cytotoxicity

Integrin-linked kinase (ILK) has been implicated as a molecular driver and mediator in both inflammation and tumorigenesis of the colon. However, a role for ILK in the tumor microenvironment (TME) and immune evasion has not been investigated. Here, we show a correlation of ILK expression with the im...

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Detalles Bibliográficos
Autores principales: Almasabi, Saleh, Boyd, Richard, Ahmed, Afsar U., Williams, Bryan R. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174997/
https://www.ncbi.nlm.nih.gov/pubmed/35692780
http://dx.doi.org/10.3389/fonc.2022.836005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174997/
https://www.ncbi.nlm.nih.gov/pubmed/35692780
http://dx.doi.org/10.3389/fonc.2022.836005

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