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Parallel Spinal Pathways for Transmitting Reflexive and Affective Dimensions of Nocifensive Behaviors Evoked by Selective Activation of the Mas-Related G Protein-Coupled Receptor D-Positive and Transient Receptor Potential Vanilloid 1-Positive Subsets of Nociceptors

The high incidence of treatment-resistant pain calls for the urgent preclinical translation of new analgesics. Understanding the behavioral readout of pain in animals is crucial for efficacy evaluation when developing novel analgesics. Mas-related G protein-coupled receptor D-positive (Mrgprd(+)) an...

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Detalles Bibliográficos
Autores principales: Wang, Liang-Biao, Su, Xiao-Jing, Wu, Qiao-Feng, Xu, Xiang, Wang, Xin-Yue, Chen, Mo, Ye, Jia-Reng, Maimaitiabula, Abasi, Liu, Xiao-Qing, Sun, Wen, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175034/
https://www.ncbi.nlm.nih.gov/pubmed/35693883
http://dx.doi.org/10.3389/fncel.2022.910670