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Comparative In vitro Metabolism of Enflicoxib in Dogs, Rats, and Humans: Main Metabolites and Proposed Metabolic Pathways

BACKGROUND: Enflicoxib is a non-steroidal anti-inflammatory drug of the coxib family characterized by a long-lasting pharmacological activity that has been attributed to its active metabolite E-6132. OBJECTIVES: The aim of this work was to explore enflicoxib biotransformation in vitro in humans, rat...

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Detalles Bibliográficos
Autores principales: Solà, Josep, Menargues, Àngel, Homedes, Josep, Salichs, Marta, Serafini, Maria Teresa, Encina, Gregorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175088/
https://www.ncbi.nlm.nih.gov/pubmed/34886785
http://dx.doi.org/10.2174/1872312814666211209161933