Conjugation of oligonucleotides with activated carbamate reagents prepared by the Ugi reaction for oligonucleotide library synthesis

The DNA-encoded library (DEL) is a powerful tool for drug discovery. As a result, to obtain diverse DELs, many DNA-compatible chemical reactions have been developed over the past decade. Among the most commonly used reactions in medicinal chemistry, multicomponent reactions (MCRs) can lead to the ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Kita, Ryosuke, Osawa, Takashi, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175101/
https://www.ncbi.nlm.nih.gov/pubmed/35755192
http://dx.doi.org/10.1039/d1cb00240f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175101/
https://www.ncbi.nlm.nih.gov/pubmed/35755192
http://dx.doi.org/10.1039/d1cb00240f

Ejemplares similares