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Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications
Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The semi-rigid PNA backbone acts as a scaffold that arranges the nucleobases in a proper orientation and spacing so that they can pair...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175113/ https://www.ncbi.nlm.nih.gov/pubmed/35755191 http://dx.doi.org/10.1039/d2cb00017b |