An Improved Genetically Encoded Fluorescent cAMP Indicator for Sensitive cAMP Imaging and Fast Drug Screening

Cyclic adenosine 3′,5′-monophosphate (cAMP) is an important intracellular second messenger molecule downstream of many G protein-coupled receptors (GPCRs). Fluorescence imaging with bright and sensitive cAMP indicators allows not only dissecting the spatiotemporal dynamics of intracellular cAMP, but...

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Detalles Bibliográficos
Autores principales: Liu, Wenfeng, Liu, Chang, Ren, Pei-Gen, Chu, Jun, Wang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175130/
https://www.ncbi.nlm.nih.gov/pubmed/35694242
http://dx.doi.org/10.3389/fphar.2022.902290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175130/
https://www.ncbi.nlm.nih.gov/pubmed/35694242
http://dx.doi.org/10.3389/fphar.2022.902290

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