Hypoxic pulmonary endothelial cells release epidermal growth factor leading to vascular smooth muscle cell arginase‐2 expression and proliferation

The hallmark of pulmonary hypertension (PH) is vascular remodeling. We have previously shown that human pulmonary microvascular endothelial cells (hPMVEC) respond to hypoxia with epidermal growth factor (EGF) mediated activation of the receptor tyrosine kinase, EGF receptor (EGFR), resulting in argi...

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Detalles Bibliográficos
Autores principales: Chen, Bernadette, Jin, Yi, Pool, Caitlyn M., Liu, Yusen, Nelin, Leif D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175134/
https://www.ncbi.nlm.nih.gov/pubmed/35674115
http://dx.doi.org/10.14814/phy2.15342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175134/
https://www.ncbi.nlm.nih.gov/pubmed/35674115
http://dx.doi.org/10.14814/phy2.15342

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