Tranilast attenuates lipopolysaccharide-induced lung injury via the CXCR4/JAK2/STAT3 signaling pathway

It has been reported that the expression of C-X-C motif chemokine receptor 4 (CXCR4) is increased in patients with lung injury, while CXCR4 downregulation can improve sepsis-induced lung injury. Previous studies have shown that tranilast can inhibit CXCR4 mRNA expression. Therefore, the present stud...

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Detalles Bibliográficos
Autores principales: Lou, Yufeng, Huang, Zhenrong, Wu, Hui, Zhou, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175269/
https://www.ncbi.nlm.nih.gov/pubmed/35583012
http://dx.doi.org/10.3892/mmr.2022.12736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175269/
https://www.ncbi.nlm.nih.gov/pubmed/35583012
http://dx.doi.org/10.3892/mmr.2022.12736

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