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Role of metformin in functional endometrial hyperplasia and polycystic ovary syndrome involves the regulation of MEG3/miR-223/GLUT4 and SNHG20/miR-4486/GLUT4 signaling

Metformin (MET) can effectively treat endometrial hyperplasia (EH), and the expression of glucose transporter type 4 insulin-responsive (GLUT4) is closely associated with the development of EH. The present study aimed to verify the effect of MET in functional EH and polycystic ovary syndrome (PCOS)....

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Detalles Bibliográficos
Autores principales: Liu, Jie, Zhao, Yangchun, Chen, Long, Li, Ruilan, Ning, Yumei, Zhu, Xiuzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175273/
https://www.ncbi.nlm.nih.gov/pubmed/35552758
http://dx.doi.org/10.3892/mmr.2022.12734