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F8 gene mutation spectrum in severe hemophilia A with inhibitors: A large cohort data analysis from a single center in China

INTRODUCTION: Type of F8 gene mutation is the most important risk factor for inhibitor development in people with severe hemophilia A. However, there are few large cohort studies on the F8 mutation spectrum of people with severe hemophilia A with inhibitors. OBJECTIVE: This was the first large cohor...

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Detalles Bibliográficos
Autores principales: Sun, Jie, Li, Zekun, Huang, Kun, Ai, Di, Li, Gang, Xie, Xingjuan, Gu, Hao, Liu, Guoqing, Zhen, Yingzi, Chen, Zhenping, Wu, Runhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175357/
https://www.ncbi.nlm.nih.gov/pubmed/35702590
http://dx.doi.org/10.1002/rth2.12723