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Blocking P2X purinoceptor 4 signalling alleviates cigarette smoke induced pulmonary inflammation
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with elevated ATP levels in the extracellular space. Once released, ATP serves as danger signal modulating immune responses by activating purinergic receptors. Accordingly, purinergic signalling has been implicated in respiratory...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175376/ https://www.ncbi.nlm.nih.gov/pubmed/35676684 http://dx.doi.org/10.1186/s12931-022-02072-z |