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Blocking P2X purinoceptor 4 signalling alleviates cigarette smoke induced pulmonary inflammation

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with elevated ATP levels in the extracellular space. Once released, ATP serves as danger signal modulating immune responses by activating purinergic receptors. Accordingly, purinergic signalling has been implicated in respiratory...

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Detalles Bibliográficos
Autores principales:	Schneider, Sven, Merfort, Irmgard, Idzko, Marco, Zech, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175376/ https://www.ncbi.nlm.nih.gov/pubmed/35676684 http://dx.doi.org/10.1186/s12931-022-02072-z

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