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Temporal regulation of interferon signalling in human EndoC-βH1 cells

During the development of type 1 diabetes, interferons (IFN) are elaborated from islet-infiltrating immune cells and/or from virally infected β-cells. They act via specific receptors to increase, acutely, the phosphorylation of the transcription factors STAT1 and 2. However, the longer-term impacts...

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Detalles Bibliográficos
Autores principales: Dhayal, Shalinee, Leslie, Kaiyven Afi, Baity, Mohammad, Akhbari, Pouria, Richardson, Sarah J, Russell, Mark A, Morgan, Noel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175560/
https://www.ncbi.nlm.nih.gov/pubmed/35521765
http://dx.doi.org/10.1530/JME-21-0224