Dysregulation of Cellular VRK1, BAF, and Innate Immune Signaling by the Vaccinia Virus B12 Pseudokinase

Poxvirus proteins remodel signaling throughout the cell by targeting host enzymes for inhibition and redirection. Recently, it was discovered that early in infection the vaccinia virus (VACV) B12 pseudokinase copurifies with the cellular kinase VRK1, a proviral factor, in the nucleus. Although the f...

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Detalles Bibliográficos
Autores principales: Linville, Alexandria C., Rico, Amber B., Teague, Helena, Binsted, Lucy E., Smith, Geoffrey L., Albarnaz, Jonas D., Wiebe, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175622/
https://www.ncbi.nlm.nih.gov/pubmed/35543552
http://dx.doi.org/10.1128/jvi.00398-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175622/
https://www.ncbi.nlm.nih.gov/pubmed/35543552
http://dx.doi.org/10.1128/jvi.00398-22

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