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Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs

Virus strains in the live attenuated influenza vaccine (LAIV) for swine in the United States that was on the market until 2020 encode a truncated nonstructural protein 1 of 126 amino acids (NS1del126). Their attenuation is believed to be due to an impaired ability to counteract the type I interferon...

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Detalles Bibliográficos
Autores principales: Vandoorn, Elien, Stadejek, Wojciech, Parys, Anna, Chepkwony, Sharon, Chiers, Koen, Van Reeth, Kristien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175629/
https://www.ncbi.nlm.nih.gov/pubmed/35546120
http://dx.doi.org/10.1128/jvi.00519-22