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RUNX inhibitor suppresses graft‐versus‐host disease through targeting RUNX‐NFATC2 axis

Patients with refractory graft‐versus‐host disease (GVHD) have a dismal prognosis. Therefore, novel therapeutic targets are still needed to be identified. Runt‐related transcriptional factor (RUNX) family transcription factors are essential transcription factors that mediate the essential roles in e...

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Detalles Bibliográficos
Autores principales: Kubota, Hirohito, Masuda, Tatsuya, Noura, Mina, Furuichi, Kana, Matsuo, Hidemasa, Hirata, Masahiro, Kataoka, Tatsuki R., Hiramatsu, Hidefumi, Yasumi, Takahiro, Nakahata, Tatsutoshi, Imai, Yoichi, Takita, Junko, Adachi, Souichi, Sugiyama, Hiroshi, Kamikubo, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175814/
https://www.ncbi.nlm.nih.gov/pubmed/35844683
http://dx.doi.org/10.1002/jha2.230