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What is the minimum adequate busulfan dose for patients with sickle cell disease undergoing reduced intensity conditioning with fludarabine, busulfan, and anti‐thymocyte globulin?

Fludarabine busulfan anti‐thymocyte globulin is a common conditioning chemotherapy with reduced toxicity used for transplantation in sickle cell disease (SCD). The dose of busulfan used in this protocol is variable across studies and centers. The minimum dose that maintains long‐term donor chimerism...

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Detalles Bibliográficos
Autores principales: AlJohani, Naif I., Toor, Amir Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175827/
https://www.ncbi.nlm.nih.gov/pubmed/35844726
http://dx.doi.org/10.1002/jha2.218