A pilot clinical phase II trial MemSID: Acute and durable changes of red blood cells of sickle cell disease patients on memantine treatment

An increase in abundance and activity of N‐methyl D‐aspartate receptors (NMDAR) was previously reported for red blood cells (RBCs) of sickle cell disease (SCD) patients. Increased Ca(2+) uptake through the receptor supported dehydration and RBC damage. In a pilot phase IIa‐b clinical trial MemSID, m...

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Detalles Bibliográficos
Autores principales: Mahkro, Asya, Hegemann, Inga, Seiler, Elena, Simionato, Greta, Claveria, Viviana, Bogdanov, Nikolay, Sasselli, Clelia, Torgerson, Paul, Kaestner, Lars, Manz, Markus G., Goede, Jeroen S., Gassmann, Max, Bogdanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Sickle Cell, Thrombosis, and Haematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175962/
https://www.ncbi.nlm.nih.gov/pubmed/35847705
http://dx.doi.org/10.1002/jha2.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175962/
https://www.ncbi.nlm.nih.gov/pubmed/35847705
http://dx.doi.org/10.1002/jha2.11

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