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Inhibition of cyclin‐dependent kinase 9 synergistically enhances venetoclax activity in mantle cell lymphoma

Mantle cell lymphoma (MCL) is an aggressive and largely incurable subtype of non‐Hodgkin's lymphoma. Venetoclax has demonstrated efficacy in MCL patients with relapsed or refractory disease, however response is variable and less durable than CLL. This may be the result of co‐expression of other...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoxian, Bodo, Juraj, Chen, Ruoying, Durkin, Lisa, Souers, Andrew J., Phillips, Darren C., Hsi, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176003/
https://www.ncbi.nlm.nih.gov/pubmed/35847704
http://dx.doi.org/10.1002/jha2.48