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Lipid-Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Components

[Image: see text] Gene editing mediated by CRISPR/Cas9 systems is due to become a beneficial therapeutic option for treating genetic diseases and some cancers. However, there are challenges in delivering CRISPR components which necessitate sophisticated delivery systems for safe and effective genome...

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Detalles Bibliográficos
Autores principales: Kazemian, Pardis, Yu, Si-Yue, Thomson, Sarah B., Birkenshaw, Alexandra, Leavitt, Blair R., Ross, Colin J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176214/
https://www.ncbi.nlm.nih.gov/pubmed/35594500
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00916