Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review

BACKGROUND: Rifamycins are a novel class of antibiotics clinically approved for tuberculosis chemotherapy. They are characterized by high inter-individual variation in pharmacokinetics. This systematic review aims to present the contribution of genetic variations in drug-metabolizing enzymes and tra...

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Detalles Bibliográficos
Autores principales: Sileshi, Tesemma, Mekonen, Gosaye, Makonnen, Eyasu, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176238/
https://www.ncbi.nlm.nih.gov/pubmed/35693129
http://dx.doi.org/10.2147/PGPM.S363058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176238/
https://www.ncbi.nlm.nih.gov/pubmed/35693129
http://dx.doi.org/10.2147/PGPM.S363058

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