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The Dihydrouridine landscape from tRNA to mRNA: a perspective on synthesis, structural impact and function

The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs. Despite its apparent simplicity, D is structurally unique, with the potential to deeply affect the RNA...

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Detalles Bibliográficos
Autores principales: Finet, Olivier, Yague-Sanz, Carlo, Marchand, Florian, Hermand, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176250/
https://www.ncbi.nlm.nih.gov/pubmed/35638108
http://dx.doi.org/10.1080/15476286.2022.2078094