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The Dihydrouridine landscape from tRNA to mRNA: a perspective on synthesis, structural impact and function
The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs. Despite its apparent simplicity, D is structurally unique, with the potential to deeply affect the RNA...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176250/ https://www.ncbi.nlm.nih.gov/pubmed/35638108 http://dx.doi.org/10.1080/15476286.2022.2078094 |