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DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m(6)A modification and translation for cytoprotective autophagy in cervical cancer

Cervical cancer (CC) is one of the most prevalent malignancies among females. Cytoprotective autophagy could confer cancer cell tolerance to hypoxic stress, promoting cell survival and adaptation. Aspartyl-tRNA synthetase 1 antisense 1 (DARS-AS1) is an oncogenic long non-coding RNA (lncRNA) in vario...

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Detalles Bibliográficos
Autores principales: Zhu, Miaohua, Shen, Weiwei, Wang, Qiming, Zhou, Xiaoming, Wang, Jiaying, Wang, Tingting, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176263/
https://www.ncbi.nlm.nih.gov/pubmed/35638109
http://dx.doi.org/10.1080/15476286.2022.2079889