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RNA polymerase inaccuracy underlies SARS-CoV-2 variants and vaccine heterogeneity
Both the SARS-CoV-2 virus and its mRNA vaccines depend on RNA polymerases (RNAP)(1,2); however, these enzymes are inherently error-prone and can introduce variants into the RNA(3). To understand SARS-CoV-2 evolution and vaccine efficacy, it is critical to identify the extent and distribution of erro...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176646/ https://www.ncbi.nlm.nih.gov/pubmed/35677076 http://dx.doi.org/10.21203/rs.3.rs-1690086/v1 |