Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice

Tyrosine-protein kinase receptor Tie2, also known as Tunica interna Endothelial cell Kinase or TEK plays a prominent role in endothelial responses to angiogenic and inflammatory stimuli. Here we generated a novel inducible Tie2 knockout mouse model, which targets mature (micro)vascular endothelium,...

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Detalles Bibliográficos
Autores principales: Zwiers, Peter J., Jongman, Rianne M., Kuiper, Timara, Moser, Jill, Stan, Radu V., Göthert, Joachim R., van Meurs, Matijs, Popa, Eliane R., Molema, Grietje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176780/
https://www.ncbi.nlm.nih.gov/pubmed/35675336
http://dx.doi.org/10.1371/journal.pone.0268986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176780/
https://www.ncbi.nlm.nih.gov/pubmed/35675336
http://dx.doi.org/10.1371/journal.pone.0268986

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