Evidence for a novel, effective approach to targeting carcinoma catabolism exploiting the first-in-class, anti-cancer mitochondrial drug, CPI-613

Clinical targeting of the altered metabolism of tumor cells has long been considered an attractive hypothetical approach. However, this strategy has yet to perform well clinically. Metabolic redundancy is among the limitations on effectiveness of many approaches, engendering intrinsic single-agent r...

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Detalles Bibliográficos
Autores principales: Guardado Rivas, Moises O., Stuart, Shawn D., Thach, Daniel, Dahan, Michael, Shorr, Robert, Zachar, Zuzana, Bingham, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176802/
https://www.ncbi.nlm.nih.gov/pubmed/35675354
http://dx.doi.org/10.1371/journal.pone.0269620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9176802/
https://www.ncbi.nlm.nih.gov/pubmed/35675354
http://dx.doi.org/10.1371/journal.pone.0269620

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